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Principal Scientist Medicinal Chemistry
Company | Bristol Myers Squibb |
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Location | San Diego, California |
Expiration | 2023-08-01 |
How to Apply | If you are interested in this job opportunity, please apply at: https://careers.bms.com/jobs/R1566928?lang=en-us&previousLocale=en-US |
Job DescriptionWorking with Us
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
Bristol Myers Squibb encompasses a broad range of disciplines to enable a robust pipeline of drug candidates aimed at serious diseases. Chemistry is a core capability in Small Molecule & Drug Discovery with innovative scientists working in medicinal chemistry, radiochemistry, analytical chemistry, and large-scale synthesis. Within SMDD our Lead Discovery and Optimization (LDO) team is responsible for high throughput screening, compound storage and distribution, primary assays to support discovery programs, and compound profiling to explore drug liabilities in vitro. LDO scientists discover and adopt cutting edge assay technologies that utilize state-of-the-art automation to drive speed and efficiency. Our Molecular Structure and Design team embraces novel approaches to computer-aided drug design, machine learning, and structural biology. The integration of these disciplines provides a seamless and highly interactive environment for discovery scientists to learn, develop, and innovate. Working in partnership with our disease area experts in the Thematic Research Centers provides an exciting pathway to discover and deliver medicines to patients in need.
Medicinal Chemistry – Principal Scientist We are seeking an exceptionally talented and highly motivated medicinal chemist who is passionate about joining our fast-paced medicinal chemistry group in the pursuit of discovering innovative therapies in Oncology. The candidate will have demonstrated an ability to design new synthetic targets independently and in a hypothesis-driven manner based on emerging SAR data. The candidate should have relevant supervisory experience with internal direct reports as well as external CROs. Candidates must have experience in the independent design and execution of multistep syntheses of complex organic molecules using modern organic chemistry. Excellent hypothesis driven problem-solving skills and a thorough understanding of medicinal chemistry principles, synthetic methods, and reaction mechanisms are required. Excellent oral and written communication skills and a desire to work in a collaborative team environment are required. A track record of innovation documented through co-inventorship on issued patents and authorship of publications in peer-reviewed journals is necessary. A strong proficiency in fundamental aspects of drug discovery and demonstrated ability to lead or co-lead multi-disciplinary discovery programs and advancing them to critical milestones is preferred. Knowledge in E3 ligase and UPS biology is a plus as protein homeostasis is one of the fundamental research engines at BMS delivering therapeutics to patients. Not being bound by therapeutic modality creates a very dynamic, exciting and creative environment where the successful chemist will interface with an excellent team of scientists in biology, biochemistry, structural biology, computational biology and translational development.
Basic Qualifications: Bachelor’s Degree and 8+ years of academic or industry experience OR Master’s Degree and 6+ years of academic or industry experience OR Ph.D. and 4+ years of academic or industry experience
Preferred Qualifications:
For California Sites - The starting compensation for this job is a range from $121,000 - $167,2700, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
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