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Senior Scientist, Neuroscience Translational Biomarker Development
Company | Bristol Myers Squibb |
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Location | San Diego, California |
Expiration | 2023-08-01 |
How to Apply | If you are interested in this job opportunity, please apply at: https://careers.bms.com/jobs/R1567927?lang=en-us&previousLocale=en-US |
Job DescriptionWorking with Us
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
The Neuroscience TRC is committed to development of transformational therapeutics for patients with neurodegenerative and neuromuscular diseases. We have built a network of external partnerships across multiple treatment modalities (small molecules, biologics and RNA targeting) that leverage our leadership in protein homeostasis and inflammation to attach neurological diseases. Internal research focuses on protein homeostasis by direct and ligand directed degradation, neuroinflammation and remyelination.
Areas of interest include, but are not limited to, the following approaches: Disease modifying therapies for neurodegenerative, neuro-inflammatory and neuromuscular diseases; CNS targets that modulate protein homeostasis, protein clearance, inflammation and reduce or eliminate toxic protein production; Emerging technologies (RNA, DNA targeting, gene regulation, editing and replacement, vector optimization) that when matched to underlying disease genetics can deliver a precision medicine portfolio with a high probability of success to address unmet medical needs; Targets in orphan/rare neurological and neuromuscular diseases. Use approaches in cellular, preclinical and translational tools and technologies such as multiomics in tissue and fluid samples to identify novel biomarkers to track neurodegenerative diseases. Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.
Position Summary: This position is based in the San Diego, CA site and reports to the Scientific Senior Director, Systems Neuroscience (in Cambridge, MA). The Senior Scientist will be part of the Neuroscience Thematic Research Center (Neuro-TRC). The emphasis will be on ensuring program team deliverables as outlined in a disciplined biomarker plan for clinical development. Consistent with the overall Neuroscience TRC externalized model, the individual may also guide one or more novel biomarker development projects. These efforts will focus on the context of use in neurodegeneration with a focus on movement disorders, including but not limited to Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and multiple sclerosis. The Senior Scientist will be interfacing with internal and external partners for the development of novel biomarkers to provide quantitative outcome measures. To accomplish these tasks, the Senior Scientist will work in the lab independently and in collaborative efforts with internal in vitro/ex vivo and in vivo groups. In addition, the Senior Scientist might also work with internal and external contractors as necessary (CROs, academics, consortia in the precompetitive space), data analysis to ultimately ensure delivery of novel biomarkers, which have a potential to deliver clinically meaningful data. The individual will also contribute to innovation projects focused on generating pilot data that informs feasibility of new outcome measures transformational to the field.
The successful candidate will have a well-established track record of constructively interacting within project sub-teams (e.g., clinical research physicians, preclinical toxicology, pharmacokinetic/pharmacodynamic line functions, statisticians, computational biologists), and with contract research organizations and other external experts to deliver science that supports the development of medicines to patients in need.
Position Responsibilities In the role as a Senior Scientist within the Systems Neuroscience group, the ideal candidate will:
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Basic Qualifications:
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Preferred Qualifications:
The starting compensation for this job is a range from $109,000.00–$150,700.00, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location. BMSNEURO #LI-Onsite
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
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