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Research Associate/Scientist, CAR-T (DAR-T)

Status: Active
CompanySorrento Therapeutics Inc.
LocationSan Diego, California
How to Apply



Sorrento Therapeutics Inc. is a fast growing, clinical stage, antibody-centric, biopharmaceutical company developing new therapies to turn malignant cancers into manageable and possibly curable diseases. Sorrento's multimodal multipronged approach to fighting cancer is made possible by its' extensive immuno-oncology platforms, including key assets such as fully human antibodies ("G-MAB™ library"), clinical stage immuno-cellular therapies ("CAR-T"), intracellular targeting antibodies ("iTAbs"), antibody-drug conjugates ("ADC"), and clinical stage oncolytic virus ("Sephrevir®").


We attract smart people who play well with others. We're small enough for your ideas to make a big impact, and large enough to offer you opportunities to grow professionally at any stage of your career.


If you’re a quick learner, enjoy working in the biotech industry, and share our mission of providing ground-breaking impact to medicine, each other, and our patients, Sorrento Therapeutics is the place for you!


Sorrento Therapeutics, Inc. is a federal government contractor and, in compliance with its obligations under current federal regulations, Sorrento requires all employees, including newly hired employees, to present proof of vaccination against COVID-19, unless the employee is legally entitled to an accommodation.  For further information, please refer to the Safer Federal Workforce Task Force’s September 24, 2021 Guidance for Federal Contractors and Subcontractors, available at:




Sorrento Therapeutics (“Sorrento”) is seeking an experienced team member with extensive expertise in molecular and cellular immunology to join our team.



We are currently seeking motivated team members with extensive expertise in molecular and cellular immunology for next generation of CAR-T/DAR-T technology and product research and development. In addition to these areas of expertise ideal candidates will have understanding of vector design, molecular cloning, CAR-T generation, and in vitro and in vivo functional assays of engineering T cells.



  •  The successful candidate will be expected to design and optimize experiments, coordinate with team members, and direct report to execute program workflows, organize and analyze results, determine appropriate follow-up experiments. 
  •  The candidate will be expected to maintain program progress according to established timelines and adjust research focus as necessary to ensure progress is on-track.
  •  The selected candidate will focus on the development of gene-editing based allogeneic product for engineered T cell immunotherapies include evaluating gene modification efficiency and their impact on potency of developed cell product.
  •  Aseptic isolation and culture of primary T cells, activation, transfection, expansion of T cells.
  •  Functional assays of T cells, cell phenotyping by FACS and designing of in vivo assays. 
  •  Excellent writing and communication skills with specific abilities to write SOP and technical reports.  




  •  For Research Associate, Bachelor's Degree in Immunology, Molecular Biology or related disciplines with minimum 1 year relevant experience or master's degree with 0-2 years relevant experience.
  •  For Scientist, PhD degree in Biochemistry, cellular biology, immunology, or a related field with 1- 3 years of related experience or master’s degree with more than 5 years related experience.
  •  Experienced with aseptic cell culture, characterization, and cell line generation.
  •  Experienced with molecular biology techniques and vector construction.
  •  Expertise in multicolor flow cytometry.
  •  Strong organizational and record keeping skills.




  •  Support scientists who are on the leading edge of immunotherapies for the treatment of cancer. 
  •  Earn a competitive salary that allows you to focus your attention on your passion.
  •  A comprehensive benefits package including: medical, dental, vision, life and disability insurance, matching 401k, company paid holidays, and Flexible PTO, plus stock options.


If this sounds like the right career to fit your personality and interests, please apply, we’re looking forward to meeting you! 


Principals only. Recruiters, please don't contact this job poster. 


Sorrento Therapeutics, Inc. is an Equal Opportunity Employer

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