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Status: Active
CompanySorrento Therapeutics
LocationSan Diego, California
How to Apply



Sorrento Therapeutics, Inc. is a clinical stage and commercial biopharmaceutical company focused on delivering innovative and clinically meaningful therapies to address unmet medical needs. Our vision is to leverage our proprietary G-MAB™ library in conjunction with proprietary targeted delivery modalities to generate the next generation of therapeutics for treating cancer, autoimmune, inflammatory, viral and neurodegenerative diseases. These modalities include proprietary chimeric antigen receptor T-cell therapy (CAR-T), dimeric antigen receptor T-cell therapy (DAR-T™), antibody drug conjugates (ADCs), oncolytic virus (Seprehvec™), lymphatic drug targeting (SOFUSA®), as well as bispecific antibody approaches. We are additionally developing pain management solutions, including our clinical candidates resiniferatoxin (RTX) and SEMDEXA™. In response to the global SARS-CoV-2 (“COVID-19”) pandemic, we are also developing and conducting clinical studies for potential coronavirus antiviral therapies and vaccines, including Abivertinib, COVI-MSC™, COVI-AMG™, COVIDROPS™, and COVI SHIELD™, and diagnostic test solutions, such as COVISTIX™ and COVITRACK™.


We attract smart people who play well with others. We're small enough for your ideas to make a big impact, and large enough to offer you opportunities to grow professionally at any stage of your career.


If you’re a quick learner, enjoy working in the biotech industry, and share our mission of providing ground-breaking impact to medicine, each other, and our patients, Sorrento Therapeutics is the place for you!


Sorrento Therapeutics, Inc. is a federal government contractor and, in compliance with its obligations under current federal regulations and guidance from the Safer Federal Workforce Task Force, Sorrento requires all employees, including newly hired employees, to present proof of vaccination against COVID-19, unless the employee is legally entitled to an accommodation.  For further information, please refer to the Safer Federal Workforce Task Force’s 2021 Guidance for Federal Contractors and Subcontractors (Updated November 10, 2021), available at:




Sorrento Therapeutics (“Sorrento”) is seeking an experienced Scientist. We are currently looking for highly motivated individuals with extensive expertise in molecular

and cellular Immunology to join group for next generation of CAR-T/DAR-T technology 

and product research and development including vector design, molecular cloning, CAR-T generation, and in vitro and in vivo functional assays of engineering T cells.  




  •  The successful candidate will be expected to design and optimize experiments, coordinate with team members, and direct report to execute program workflows, organize and analyze results, determine appropriate follow-up experiments. 
  • The candidate will be expected to maintain program progress according to established timelines and adjust research focus as necessary to ensure progress is on-track.
  • The selected candidate will focus on the development of gene-editing based allogeneic product for engineered T cell immunotherapies include evaluating gene modification efficiency and their impact on potency of developed cell product.
  • Aseptic isolation and culture of primary T cells, activation, transfection, expansion of T cells.
  • Functional assays of T cells, cell phenotyping by FACS and designing of in vivo assays. 
  • Excellent writing and communication skills and can write SOP and technical reports.  




  • Ph.D. degree in biochemistry, cell biology, immunology or a related field with 1- 3 years of related experience or Master’s degree with more than 5 years of related experience.
  • Experience with aseptic cell culture, characterization and cell line generation.
  • Hands-on experience with various molecular biology techniques and vector construction.
  • Proficiency with multicolor flow cytometry and cell sorting is preferred.
  • Previous experience with functional assays (ELISA, cell reporter and cytotoxicity assays, etc.) is a plus, but not required.
  • Strong organizational, record-keeping skills and attention to details.




  •  Support scientists who are on the leading edge of immunotherapies for the treatment of cancer. 
  •  Earn a competitive salary that allows you to focus your attention on your passion.
  •  A comprehensive benefits package including: medical, dental, vision, life and disability insurance, matching 401k, company paid holidays, and Flexible PTO, plus equity-based compensation.


If this sounds like the right career to fit your personality and interests, please apply, we’re looking forward to meeting you! 


Principals only. Recruiters, please do not contact this job poster. 


Sorrento Therapeutics, Inc. is an Equal Opportunity Employer.

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