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Protein Engineering Director

Status: Active
CompanyNeologics Bio
LocationSuzhou, China
Expiration2023-05-16
How to Apply

Please send your resume to: lin.chen@neologicsbio.com

Responsibilities 职责

 

  1. As an expert in protein engineering, you are expected to engineer different leading molecules including but not limited to antibodies, bi-specific antibodies, multiplexities, cytokines, and fusion proteins to generate tools and participate in target discovery/validation activities.

蛋白质工程专家,负责并精通各种蛋白工程,包括抗体,双抗,融合蛋白,细胞因子等等。

  1. Oversee daily operations of the antibody engineering of each project, including sequence and structure-based analysis and modeling, sequence optimization, affinity maturation, humanization, multiple specific antibody design and generation.

负责公司所有项目蛋白质工程的一切事物,包括序列优化,亲和力成熟,人源化,双抗多功能抗体的设计和表达。

  1. Identify and implement new technologies/platforms to improve the quality and speed of antibody engineering process to meet company goals.

发现,学习跟进,并采纳可以提高抗体质量、优化抗体的技术。

  1. Develop novel technologies/platforms including multispecifc platforms.

开发双抗和多抗平台。

  1. Design and implement functional and cell-based assays to support antibody engineering efforts. Build strong working relationships with fellow Neologics Bio colleagues, key external advisors and collaborators.

开发测试蛋白设计质量方面的检测方法。团队协作,外部专家协作,商务合作支持。

  1. Lead, manage and develop a high performing team of protein/antibody engineers with varied specialty areas including MoA elucidation, display technologies, protein chemistry, structural biology, and assay development.

管理领导蛋白质工程团队,包括擅长各种领域的小分队。

  1. The role will require close collaboration with the Bioinformatics and Discovery Biology groups to ensure successful progression of pipeline projects ranging from pre-clinical discovery to clinical proof-of-concept.

和生物信息,抗体发现团队密切合作。

 

Qualifications 任职要求

 

  1. PhD in Biochemistry/Molecular Biology/Structural Biology or related disciplines with at least 5 years relevant industry experience in a biopharmaceutical setting.

生物化学/分子生物学/结构生物学及相关领域Ph.D, 5年以上工作经验。

  1. Extensive experience in protein/Ab engineering, structural biology and bispecific antibody design and engineering with a proven track record of innovative solutions.

在抗体蛋白工程,结构生物学,双抗的设计有丰富经验和可靠经验记录。

  1. Extensive knowledge in variety of protein engineering platforms and technologies.

丰富的蛋白工程各种平台的知识。

  1. Experience in leading programs at all stages of biologics drug discovery from lead generation to candidate nomination.

抗体药发现各种技术平台的知识和技能。

  1. Strong communication, organizational, leadership and interpersonal skills.

交流协调,领导能力。

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